BOSTON — Animal Biosciences, a company that seeks to extend the lives of pets, shared the latest clinical research on their Leap Years dog supplement on Feb. 29, showing that Leap Years can help reverse age-related decline in dogs, as well as significantly improve cognitive function.
Leap Years is a soft chew supplement that consists of an NAD+ Precursor and a senolytic, a small molecule used to kill senescent cells that cause aging. The supplement specifically targets aging, which can lead to the deterioration of tissues and organ function. According to Animal Biosciences, older dogs experience cognitive decline, increased frailty and lower interaction, just like humans. To help reverse these effects of aging, Animal Biosciences developed the supplement, which underwent five years of development and testing using discoveries from Harvard Medical School.
The double-blind clinical study was conducted at the North Carolina State University (NCSU) Veterinary College in collaboration with Natasha Olby, Ph.D., professor of neurology and neurosurgery. This confirms that Leap Years can improve cognitive function and has shown positive effects on other areas of decline, such as vulnerability, activity and happiness. It was published on BioRxiv, a preprint server for biology.
“The clinical trial results, especially the cognitive improvements, are encouraging and represent a remarkable achievement,” Olby said. “This rigorous study, which recognizes the difficulties of aging pets and their owners, demonstrates our dedication to scientific methods aimed at improving the quality of life for our companions in dog.”
According to Animal Biosciences, this study presents “the first clinical evidence that it is possible to reverse age-related decline in dogs.”
“I am extremely proud of the teams at NCSU and Animal Biosciences, who, after years of collaborative research and a clinical trial, have developed the first supplement proven to reverse aging in dogs,” said David A. Sinclair , AO, Ph.D ., professor of genetics at Harvard Medical School and co-founder of Animal Biosciences.
Animal Biosciences was founded in 2017 by David A. Sinclair and his brother Nick Sinclair, chief executive officer. The company applies small molecule-based therapy from the human health industry to the pet industry with the goal of delaying aging and extending the healthy lives of pets.
Read the full Leap Years study here.
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